Endocrine Abstracts

Glomerular podocytes are directly regulated by insulin (1) and podocyte insulin resistance is implicated in diabetic kidney disease. Information theory derived statistical measures can be used to quantify information transfer via cell signalling pathways (2). This novel approach takes into account cell-cell variation in responses and the impact that this noise has on information transfer but has not yet been applied to signalling in podocytes. Here we quantify the mutual infor...